77. A pharmacy must utilize a DEA Form 222 or CSOS to order:

Answer: D

Explanation:

A pharmacy must utilize a DEA Form 222 or CSOS to order Hydromorphone.

Hydromorphone is a controlled substance that requires a DEA Form 222 or Controlled Substance Ordering System (CSOS) for ordering due to its classification as a Schedule II drug, which has strict regulations on its distribution and handling.

A) Guaifenesin/codeine

Guaifenesin/codeine is a combination medication that contains codeine, which is a Schedule III controlled substance. While it does require a prescription, it does not necessitate the use of a DEA Form 222 or CSOS for ordering, making this option incorrect.

B) Acetaminophen/codeine

Acetaminophen/codeine is also a combination medication classified as a Schedule III controlled substance. Similar to Guaifenesin/codeine, it requires a prescription but does not require a DEA Form 222 or CSOS for ordering, thus making this option incorrect.

C) Naloxone

Naloxone is an opioid antagonist used to counteract opioid overdoses and is not classified as a controlled substance. Therefore, it does not require a DEA Form 222 or CSOS for ordering, which renders this option incorrect.

D) Hydromorphone

Hydromorphone is classified as a Schedule II controlled substance. As such, it requires a DEA Form 222 or Controlled Substance Ordering System (CSOS) for ordering, making this option the correct choice.

Conclusion

Hydromorphone is the only medication among the options that is classified as a Schedule II controlled substance, necessitating the use of a DEA Form 222 or CSOS for ordering. The other options, being either Schedule III or non-controlled substances, do not have the same regulatory requirements, confirming that Hydromorphone is the only correct answer in this context.