77. A pharmacy must utilize a DEA Form 222 or CSOS to order:

Answer: D

Explanation:

Pharmacy must utilize a DEA Form 222 or CSOS to order Hydromorphone.

Hydromorphone requires a DEA Form 222 or Controlled Substance Ordering System (CSOS) for ordering due to its classification as a Schedule II controlled substance.

A) Guaifenesin/codeine

Guaifenesin/codeine is a combination medication that contains codeine, which is a Schedule III controlled substance. Therefore, it does not require a DEA Form 222 or CSOS for ordering, making this option incorrect.

B) Acetaminophen/codeine

Acetaminophen/codeine is also classified as a Schedule III controlled substance. Like guaifenesin/codeine, it does not require a DEA Form 222 or CSOS for ordering, thus rendering this option incorrect as well.

C) Naloxone

Naloxone is not classified as a controlled substance; it is used to reverse opioid overdoses. Consequently, it does not require a DEA Form 222 or CSOS for ordering, making this option incorrect too.

D) Hydromorphone

Hydromorphone is classified as a Schedule II controlled substance, which necessitates the use of a DEA Form 222 or CSOS for ordering. This makes it the correct answer to the question.

Conclusion

Hydromorphone is the only substance listed that requires a DEA Form 222 or CSOS for ordering due to its Schedule II classification. The other options, being either Schedule III substances or non-controlled substances, do not have the same regulatory requirements, which clearly distinguishes Hydromorphone as the correct choice.