77. A pharmacy receives the following prescriptions: Donepezil 5 mg #28, 1 tablet by mouth daily for 4 weeks, then increase to Donepezil 10 mg #30, 1 tablet by mouth daily thereafter, 5 refills. The prescriptions are both dispensed, and the patient is hospitalized after several weeks. The patient responds poorly. Which of the following strategies would have best helped to prevent similar errors in the future?

Answer: D

Explanation:

Dispensing the donepezil 5 mg prescription first and the donepezil 10 mg prescription separately after the 4-week titration period.

This strategy ensures that the patient takes the correct dosage at each stage of their treatment plan. By separating the prescriptions based on the titration schedule, it minimizes the risk of confusion and potential overdosing.

A) Having a pharmacy technician counsel the patient regarding how to take their medication

While counseling is an important aspect of medication safety, it does not directly address the issue of titration and the timing of medication changes. If the prescriptions are not dispensed correctly according to the titration plan, counseling alone may not prevent errors.

B) Dispensing #58 donepezil 10 mg tablets and updating the instructions for the patient

This option could lead to potential overdosing, as it disregards the titration schedule outlined in the prescription. The patient is supposed to take the lower dose for the first four weeks, and providing the higher dose prematurely could have detrimental effects on their health.

C) Placing auxiliary labels on the vials to indicate that the 10 mg tablets should be taken

Although auxiliary labels can provide helpful reminders, they do not replace the need for proper dispensing practices. If the prescriptions are filled incorrectly, even the best labeling will not prevent the patient from taking the wrong dosage at the wrong time.

D) Dispensing the donepezil 5 mg prescription first and the donepezil 10 mg prescription separately after the 4-week titration period.

This is the most effective strategy as it adheres to the prescribed titration plan. By dispensing the medications separately, the pharmacy ensures that the patient follows the intended schedule, reducing the risk of medication errors and adverse effects.

Conclusion

Dispensing the donepezil 5 mg prescription first and the donepezil 10 mg prescription separately after the 4-week titration period is the only option that fully aligns with the prescribed treatment plan. All other options either fail to address the titration schedule or introduce risks of administering incorrect dosages, highlighting the importance of adhering to specific medication protocols to ensure patient safety.