Question 57

Equipment and utensils used for nonsterile compounding should not be reactive, additive, or sorptive.

In accordance with USP Chapter 795, it is essential that equipment and utensils utilized in nonsterile compounding do not interact chemically with the compounds being prepared. This ensures that the final product maintains its integrity and effectiveness.

A) affect the purity of the product

This option is incorrect because equipment and utensils should not affect the purity of the product. In fact, they should be designed to ensure that the purity is preserved, thereby avoiding any contamination or alteration of the compounding materials.

B) not be reactive, additive, or sorptive

This option is correct as it aligns directly with the guidelines of USP Chapter 795. Equipment and utensils must not react with the compounds, add any substances to them, or absorb components, ensuring that the compound's quality remains intact.

C) adhere to USP Chapter 797 guidelines as well

While adherence to USP Chapter 797 is important for sterile compounding, this option is irrelevant in the context of nonsterile compounding as outlined in USP Chapter 795. The focus here is specifically on nonsterile practices, making this option incorrect.

D) not be made of glass or porcelain

This option is misleading and incorrect. While certain materials may be preferred for specific applications, there is no blanket prohibition against using glass or porcelain in nonsterile compounding. The critical factor is that the materials must not be reactive, additive, or sorptive.

Conclusion

The correct answer is B, as it emphasizes the importance of using non-reactive, non-additive, and non-sorptive materials in nonsterile compounding to preserve product quality. The other options either misinterpret the guidelines or focus on irrelevant aspects, underscoring the necessity of proper material selection to ensure compounding safety and efficacy.