14. Cimetidine 400 mg tablet b.i.d. â†' liquid 300 mg/5 mL. Volume per dose?

Answer: B

Explanation:

The volume per dose of Cimetidine liquid is 6.7 mL.

To find the volume per dose of Cimetidine liquid, we need to calculate the total daily dosage and then determine how much liquid corresponds to that dosage. Given that Cimetidine is prescribed at 400 mg twice daily, the total daily dosage is 800 mg. Since the liquid formulation contains 300 mg per 5 mL, we can calculate the required volume for 800 mg.

A) 1.3

This option represents an incorrect volume for the liquid dose. Given the total daily dosage of 800 mg and the concentration of the liquid, this volume would be insufficient to provide the necessary 800 mg of Cimetidine.

B) 6.7

This is the correct answer. To achieve the total daily dosage of 800 mg, one would need approximately 6.7 mL of the Cimetidine liquid, as the calculation shows that 800 mg corresponds to 6.7 mL when using the concentration of 300 mg per 5 mL.

C) 7.6

Option C is incorrect as it suggests a higher volume than necessary for the required dose. This volume does not accurately reflect the calculation based on the total daily requirement and the concentration of the liquid formulation.

D) 13.3

This option is also incorrect. It indicates an excessively high volume for the liquid dose, which far exceeds the amount needed to provide the total daily dosage of 800 mg of Cimetidine.

Conclusion

The volume per dose of 6.7 mL is derived from the proper calculation based on the prescribed dosage and the concentration of the Cimetidine liquid formulation. All other options fail to meet the required volume to deliver the correct total daily dosage, confirming that B is the only accurate choice.