21. Which of the following is an ACE inhibitor?
Answer: B
Fosinopril is an ACE inhibitor.
Fosinopril is classified as an ACE (Angiotensin-Converting Enzyme) inhibitor, which is a type of medication used primarily for the treatment of high blood pressure and heart failure.
A) Nifedipine
Nifedipine is not an ACE inhibitor; it is a calcium channel blocker that works by relaxing blood vessels to lower blood pressure. It does not inhibit the angiotensin-converting enzyme, which is the mechanism of action for ACE inhibitors.
B) Fosinopril
Fosinopril is indeed an ACE inhibitor, functioning by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This action helps to lower blood pressure and reduce the workload on the heart, making it effective in treating hypertension and heart failure.
C) Fluoxetine
Fluoxetine is an antidepressant belonging to the selective serotonin reuptake inhibitors (SSRIs) class. It does not have any role as an ACE inhibitor and is used primarily to treat depression and anxiety disorders.
D) Donepezil
Donepezil is a medication used to treat Alzheimer's disease by inhibiting the enzyme acetylcholinesterase. It does not act on the angiotensin-converting enzyme and therefore is not classified as an ACE inhibitor.
Conclusion
Fosinopril stands out as the correct answer because it is specifically designed to inhibit the angiotensin-converting enzyme, which is critical for managing conditions like hypertension. The other options, Nifedipine, Fluoxetine, and Donepezil, do not share this mechanism of action, confirming that they are not ACE inhibitors.