33. Which of the following is an IV medication that has a narrow therapeutic index and requires periodic laboratory monitoring to prevent patient harm?
Answer: D
Vancomycin is an IV medication that has a narrow therapeutic index and requires periodic laboratory monitoring to prevent patient harm.
Vancomycin is known for its narrow therapeutic index, meaning there is a small margin between effective and toxic doses. Therefore, regular laboratory monitoring of drug levels is essential to ensure patient safety and efficacy.
A) Varenicline
Varenicline is primarily used as a smoking cessation aid and is not classified as an IV medication. It does not have a narrow therapeutic index, nor does it require routine laboratory monitoring, making it an incorrect choice.
B) Venlafaxine
Venlafaxine is an oral antidepressant that does not qualify as an IV medication. It does not have a narrow therapeutic index, and while it may require monitoring for certain side effects, it is not monitored through laboratory tests in the same manner as vancomycin.
C) Valacyclovir
Valacyclovir is an antiviral medication typically administered orally and does not require intravenous administration. It also does not have a narrow therapeutic index nor necessitates routine laboratory monitoring, disqualifying it from being the correct answer.
D) Vancomycin
Vancomycin is an intravenous antibiotic with a narrow therapeutic index, making it critical to monitor serum levels to avoid toxicity. Its use in treating serious infections necessitates careful laboratory oversight, confirming it as the correct answer.
Conclusion
Vancomycin stands out as the only option that meets the criteria of being an IV medication with a narrow therapeutic index requiring regular laboratory monitoring. The other options either do not involve intravenous administration, lack a narrow therapeutic index, or do not necessitate laboratory monitoring, solidifying vancomycin as the definitive correct answer.