64. Which of the following medications may be crushed prior to administration?
Answer: D
Sucralfate may be crushed prior to administration.
Sucralfate is a medication that can be safely crushed before administration, making it suitable for patients who have difficulty swallowing tablets.
A) Risedronate
Risedronate is a bisphosphonate used to treat osteoporosis and should not be crushed. Crushing can alter its absorption and effectiveness, potentially leading to decreased efficacy and increased risk of side effects.
B) Bupropion XL
Bupropion XL is an extended-release formulation that must not be crushed. Crushing this medication can lead to a rapid release of the drug into the system, increasing the risk of adverse effects and toxicity.
C) Diltiazem ER
Diltiazem ER is an extended-release medication that is designed to be released slowly into the bloodstream. Crushing this tablet disrupts the extended-release mechanism, leading to a rapid increase in drug levels that can be harmful.
D) Sucralfate
Sucralfate can be crushed before administration without affecting its therapeutic properties. It is often prescribed to treat ulcers and can be taken in a form that is easier to swallow, making it the correct choice among the options.
Conclusion
Sucralfate is the only medication listed that can be crushed prior to administration without compromising its effectiveness or safety. In contrast, risedronate, bupropion XL, and diltiazem ER are all extended-release or modified-release medications that must remain intact to ensure proper absorption and minimize risks to the patient.